The Science behind African Mango

Leptin Resistance is the reason that many overweight people cannot lose weight. African Mango Seed Extract, scientifically known as IGOB131, may correct Leptin Resistance, helping people lose weight naturally, safely and effectively.

Leptin is a hormone produced by Adipocytes, which are similar to fat cells, and has two key roles within the human body. Leptin binds to your hypothalamus, the part of the brain that controls hunger, and sends signals to the rest of the body to stop eating when you are full. Its second role is to help the body use stored fat as energy.

Because leptin reduces appetite and burns fat, you would think that the key to weight loss would be to increase leptin levels. On the contrary, studies have found that overweight people tend to have higher leptin levels than people of average weight.

So why doesn't leptin help overweight people lose weight?

Overweight people tend to exhibit leptin resistance. The more a person eats, the more leptin the brain produces to tell the person to stop eating. This overloads the receptors in the brain and on the fat cells themselves. Once the receptors are overloaded, they become Leptin Resistant, and stop responding to the leptin. Once a person becomes Leptin Resistant, their fat cells start to get larger, their ability to burn fat decreases, their hunger remains and their weight begins to increase.

Leptin Resistance is the one of the reasons why so many overweight people have trouble losing weight. African Mango Seed Extract (IGOB131) may help correct Leptin Resistance.

Research has shown that people with Leptin Resistance have high levels of C-reactive protein or CRP. Too much CRP in the body is major factor contributing to Leptin Resistance. Studies have shown that IGOB131 can decrease CRP levels by 52% over 10 weeks. That drop in CRP makes the body more responsive to leptin. Increased response to leptin means the person will feel full faster and their body will burn fat more easily.

African Mango Seed Extract helps correct Leptin Resistance but that is not all that it can do. Studies have shown that IGOB131 can increase the body's levels of adiponectin, a hormone that has been shown to have anti-inflammatory and positive weight loss effects. IGOB131 is also believed to inhibit amylase production. Inhibited amylase production causes the body to take longer to convert carbohydrates into simple sugars. This leads to improved insulin levels and a lower glycemic index. Finally, IGOB131 has also been shown to help inhibit the production of glycerol-3-phosphate dehydrogenase, an enzyme that helps convert sugar to stored fat. All of the above factors help African Mango Seed Extract contribute to healthy, natural weight loss.

Important African Mango Information